Dr. Dana Ishay-Ronen, MD PhD

Dr. Dana Ishay-Ronen

Dr. Dana Ishay-Ronen, MD PhD


Ishay-Ronen’s research group studies cancer cell plasticity and trans-differentiation therapeutic approaches using patient-derived organoids.


Dr. Dana Ishay-Ronen is M.D. from the Medical University of Vienna, Austria and Ph.D. in Cell Biology from the University of Basel, Switzerland. During her Ph.D. Dr. Ishay-Ronen developed a novel therapeutic approach to target aggressive breast cancer cells by forcing their trans-differentiation into non-dividing fat cells. Currently a resident in Oncology, Dr. Ishay-Ronen participates in a physician-scientist program at the Sheba medical center.


Her research focuses on translational research towards the establishment of the trans-differentiation strategy as a treatment approach for cancer patients. Utilizing patient-derived organoid culture methods from cancer and normal tissues, the Ishay-Ronen research group studies regulatory mechanisms of cell plasticity during tumorigenesis and cancer progression.  


Contact info:

Dr. Dana Ishay-Ronen, MD PhD

Oncology Institute, Sheba Medical Center

Sheba physician-scientist program


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