Molecular biology of the insulin-like growth factors.
Prof. Werner’s lab is focusing in the understanding the molecular and cellular events responsible for IGF1R expression in cancer.
The insulin-like growth factors (IGF1, IGF2) are a family of hormones with important roles in growth and development.
The biological actions of the IGFs are mediated by the IGF1 receptor (IGF1R), a cell-surface receptor related to the insulin receptor.
These studies are expected to generate information that might translate into more efficient IGF1R targeting approaches.
A better understanding of the molecular biology of the IGF system will have important ramifications in areas such as obesity, diabetes and cancer research.
Prof. Haim Werner, PhD
Sackler Faculty of Medicine