Dr. Cohen lab focuses on dissecting the intercellular communication between immune cells and tissue resident cells in the tumor microenvironment. Recent genomic and proteomic technology advances have led to breakthroughs in our understanding of single cell states, and the cellular composition of complex environments, such as the tumor microenvironment; however, molecular characteristics of interacting cells are still missing.
Dr. Cohen lab incorporates state of the art single cell RNA-sequencing technologies, murine models, clinical approaches and advanced computational methods in order to reveal the molecular signature of interacting cells that drives exclusive cell function. The lab aims to assess similarities and discrepancies in interactome molecular signature between tissue development process and cancerous conditions in order to identify novel immunotherapy targets, directed against intercellular crosstalk.
Contact Info:
